EN PT

Selected Publications Between 2018 & 2023

“Overcoming challenges of infrared photosensitizers in Photodynamic Therapy: The making of redaporfin”

L. G. Arnaut, M. M. Pereira Chem. Commun., 59 (2023)
DOI: 10.1039/D3CC02283H

“Selective, broad-spectrum antiviral photodynamic disinfection with dicationic imidazolyl chlorin photosensitizers”

Z. A. Arnaut, S. M. A. Pinto, R. T. Aroso, A. S. Amorim, C. S. Lobo, F. A. Schaberle, D. Pereira, J. Núñez, S. C. C. Nunes, A. A. C. C. Pais, P. Rodrigues-Santos, L. P. Almeida, M. M. Pereira, L. G. Arnaut. Photochem. Photobiol. Sci., 22 (2023) 2607-2620.
DOI: 10.1007/s43630-023-00476-4

“Photodynamic therapy changes tumour immunogenicity and promotes immune-checkpoint blockade response, particularly when combined with micromechanical priming”

C. S. Lobo, M. I. P. Mendes, D. A. Pereira, L. C. Gomes-da-Silva, L. G. Arnaut. Sci. Rep., 13 (2023) 11667
DOI: 10.1038/s41598-023-38862-8

“Interaction of two commercial azobenzene food dyes, amaranth and new coccine, with human serum albumin: Biophysical characterization”

O. A. Chaves, R. J. S. Loureiro, A. Costa-Tuna, Z. L. Almeida, J. Pina, R. M. M. Brito, C. Serpa. ACS Food Sci. Tech. 3 (2023) 955-968
DOI: 10.1021/acsfoodscitech.3c00125

“Ultrathin materials for wide bandwidth laser ultrasound generation: titanium dioxide nanoparticle films with adsorbed dye”.

T. B. Pinto, S. M. A. Pinto, A. P. Piedade, C. Serpa. Nanoscale Adv. 5 (2023) 4191-4202
DOI: 10.1039/D3NA00451A 

“Antitumor Immunity Mediated by Photodynamic Therapy Using Injectable Chitosan Hydrogels for Intratumoral and Sustained Drug Delivery”

Piotr Gierlich, Claire Donohoe, Kevin Behan, Daniel J Kelly, Mathias O Senge, Lígia C Gomes-da-Silva. Biomacromolecules 25 (2023) 24-42
DOI: 10.1021/acs.biomac.3c00591

“Strapped Porphyrins as Model Systems for Atropisomeric Photosensitizer Drugs”

C. Donohoe, A. Charisiadis, S. Maguire, B. Twamley, F. A. Schaberle, L. C. Gomes-da-Silva, M. O. Senge. Eur. J. Org. Chem. 26 (2023) e202201453
DOI: 10.1002/ejoc.202201453

“Trial Watch: An update of clinical advances in photodynamic therapy and its immunoadjuvant properties for cancer treatment”

M. Penetra, L. G. Arnaut, L. C. Gomes-da-Silva, OncoImmunol., 12 (2023) 2226535
DOI: 10.1080/2162402X.2023.2226535

“Redaporfin Development for Photodynamic Therapy and its Combination with Glycolysis Inhibitors”

M. I. P. Mendes, L. G. Arnaut, Photochem. Photobiol., 99 (2023) 769-776.
DOI: 10.1111/php.13770

“Nanodroplet vaporization with pulsed-laser excitation repeatedly amplify photoacoustic signals at low vaporization thresholds”

M. I. P. Mendes, C. D. F. Coelho, F. A. Schaberle, M. J. Moreno, M. J. F. Calvete, L. G. Arnaut. RSC Adv., 13 (2023) 35040-35049.
DOI: 10.1039/D3RA05639B

“Unravelling the pivotal role of atropisomerism for cellular internalization”

C. Donohoe, F. A. Schaberle, F. M. S. Rodrigues, N. Gonçalves, C. J. Kingsbury, M. M. Pereira, M. O. Senge, L. C. Gomes-da-Silva, L. G. Arnaut, J. Am. Chem. Soc., 144 (2022) 15252-15265.
DOI: 10.1021/jacs.2c05844

“Photodynamic disinfection of SARS-CoV-2 clinical samples using a methylene blue formulation”

C. S. Lobo, P. Rodrigues-Santos, D. Pereira, J. Núñez, J. C. D. Trêpa, D. L. Sousa, J. V. Lourenço, M. F. Coelho, L. P. Almeida, J. S. Cunha, L. G. Arnaut, Photochem. Photobiol. Sci., 21 (2022) 1101-1109.
DOI: 10.1007/s43630-022-00202-6

“Photodynamic disinfection and its role in controlling infectious diseases”

R. T. Aroso, F. A. Schaberle, L. G. Arnaut, M. M. Pereira, Photochem. Photobiol. Sci., 20 (2021) 1497-1545
DOI: 10.1007/s43630-021-00102-1

“Imaging of photoacoustic-mediated permeabilization of giant unilamellar vesicles (GUVs)”

D. A. Pereira, A. D. Silva, P. A. T. Martins, A. P. Piedade, D. Martynowych, D. Veysset, M. J. Moreno, C. Serpa, K. A. Nelsen, L. G. Arnaut, Sci. Rep., 11 (2021) 2775.
DOI: 10.1038/s41598-021-82140-4

“Using amyloid autofluorescence as a biomarker for lysozyme aggregation inhibition”

C. S.H. Jesus, H. T. Soares, A. P. Piedade, L. Cortes, C. Serpa. Analyst,. 146 (2021) 2383-2391
DOI: 10.1039/D0AN02260H

“Photoacoustic generation of intense and broadband ultrasound pulses with functionalized carbon nanotubes”

A. D. Silva, C. A. Henriques, D. V. Malva, M. J. F. Calvete, M. M. Pereira, C. Serpa, L. G. Arnaut, Nanoscale, 12 (2020) 20831-20839.
DOI: 10.1039/d0nr04986g

“Self-sustained oscillations and global climate changes”

L. G. Arnaut, S. Ibáñez, Sci. Rep., 10 (2020) 11200.
DOI: 10.1038/s41598-020-68052-9

“Necrosis depth and photodynamic therapy threshold dose with redaporfin-PDT”

L. B. Rocha, H. T. Soares, M. I. P. Mendes, A. Cabrita, F. A. Schaberle, L. G. Arnaut, Photochem. Photobiol., 96 (2020) 692-698.
DOI: 10.1111/php.13256.

“Antibacterial photodynamic inactivation of antibiotic-resistant bacteria and biofilms with nanomolar photosensitizer concentrations”

C. S. Vinagreiro, A. Zangirolami, F. A. Schaberle, S. C. C. Nunes, K. C. Blanco, N. M. Inada, G. Jorge da Silva, A. A. C. C. Pais, V. S. Bagnato, L. G. Arnaut, M. M. Pereira, ACS Infect. Dis, 6 (2020) 1517-1526.
DOI: 10.1021/acsinfecdis.9b00379.

“Regulatory approval of photoimmunotherapy: photodynamic therapy that induces immunogenic cell death”

L. C Gomes-da-Silva, O. Kepp, G. Kroemer. Oncoimmunology .9 (2020) 1841393.
DOI: 10.1080/2162402X.2020.1841393

“Cell death in photodynamic therapy: from oxidative stress to anti-tumor immunity”

C. Donohoe, M. Senge, L. G. Arnaut, L. C. Gomes-da-Silva, BBA Rev. Cancer, 1872 (2019) 188308.
DOI: 10.1016/j.bbcan.2019.07.003.

“Photon momentum transfer at water/air interfaces under total internal reflection”

F. A. Schaberle, L. A. Reis, C. Serpa, L. G. Arnaut, New J. Phys., 21 (2019) 049501. Corrigendum: New J. Phys., 21 (2019) 049501.
DOI: 10.1038/s41598-018-37759-1

“Photoacoustic transfection of DNA encoding GFP”

A. D. Silva, C. Serpa, L. G. Arnaut, Sci. Rep., 9 (2019) 2553.
DOI: 10.1038/s41598-018-37759-1

“Recruitment of LC3 to damaged Golgi apparatus”

L. C. Gomes-da-Silva, A. J. Jimenez, A. Sauvat, W. Xie, S. Souquere, S. Divoux, M. Storch, B. Sveinbjørnsson, Ø. Rekdal, L. G. Arnaut, O. Kepp, G. Kroemer, F. Perez, Cell Death Diff.., 26 (2019) 1467-1484.
DOI: 10.1038/s41418-018-0221-5

“Split-face, randomized, placebo-controlled, double-blind study to investigate passive versus active dermal filler administration”

M. J. Freire-dos-Santos, R. Carvalho, L. G. Arnaut, Aesth. Plast. Surg., 42 (2018) 1655-1663
DOI: 10.1007/s00266-018-1208-9 

“Redaporfin induces immunogenic cell death by selective destruction of the endoplasmic reticulum and the Golgi apparatus”

L. C. Gomes-da-Silva, L. Zhao, L.G. Arnaut, G. Kroemer, O. Kepp, Oncotarget., 9 (2018) 31169-31170.
DOI: 10.18632/oncotarget.25798

“Higher Activation Barriers Lift Exothermic Rate Restrictions in Electron Transfers and Enable Faster Reactions”

K. K. Mentel, A. Serra, P. Abreu, L. G. Arnaut, Nature Commun., 9 (2018) 2903.
DOI: 10.1038/s41467-018-05267-5

“Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus”

L. C. Gomes-da-Silva, L. Zhao, H. Zhou, A. Sauvat, P. Liu, L. Bezu, S. Durand, M. Leduc, G. Pierron, F. Loos, B. Sveinbjørnsson, Ø. Rekdal, G. Boncompain, F. Perez, L.G. Arnaut, O. Kepp, G. Kroemer, EMBO J., 37 (2018) e98354.
DOI: 10.15252/embj.201798354

“Translating phototherapeutic indices from in vitro to in vivo photodynamic therapy with bacteriochlorins”

A. F. S. Luz, B. Pucelik, M. M. Pereira, J. M. Dabrowski, L. G. Arnaut, Lasers Surg. Med., 50 (2018) 451-459.
DOI: 10.1002/lsm.22931.

“One peptide reveals the two faces of a a-helix unfolding-folding dynamics”

C. S. H. Jesus, P. F. Cruz, L. G. Arnaut, R. M. M. Brito, C. Serpa, J. Phys. Chem. B, 122 (2018) 3790–3800.
DOI: 10.1021/acs.jpcb.8b00229